Gut Taste Mechanism Defective in Type 2 Diabetes Patients

Depression with diabetes may speed mental decline

In 2007, diabetes was the seventh leading cause of death in the U.S. To proceed with the finding, the researchers compared healthy adults with type 2 diabetes patients. On glucose exposure, they noticed that in healthy adults, the control of sweet taste receptors in the intestine enabled their bodies to regulate the glucose intake in 30 minutes after exposure whereas abnormalities in diabetic adults led to rapid absorption of glucose. On detecting the glucose in the intestine, the sweet taste receptors trigger a response that regulates the manner in which glucose is taken by the intestine. The researchers noticed that compared to healthy adults, the diabetes victims absorbed more glucose rapidly and in large quantities. The study highlights that diabetes is not a disorder that is limited to pancreas and insulin, the gut too plays an effective role.
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More than one-quarter of Americans older than age 65 have diabetes, according to the Centers for Disease Control and Prevention. An estimated 6.5 million Americans in this age group suffer from depression, according to the National Alliance for Mental Illness. To assess the role of depression in cognitive decline among older diabetes patients, Sullivan’s team looked at data on nearly 3,000 people over age 55 with type 2 diabetes and risk factors for cardiovascular events. On average, participants had had diabetes for about 9 years. Tests of cognitive abilities were given to all participants at the study’s beginning, and again at 20 months and 40 months. One test measured psychomotor speed, or how long it takes the brain to register a stimulus, process it and respond.
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